Duchenne muscular dystrophy – Common signs and diagnosis

Duchenne muscular dystrophy – Common signs and diagnosis

Duchenne muscular dystrophy (DMD) is a rare genetic disorder that affects muscle strength and mobility. It commonly affects young boys, with symptoms developing during early infancy or childhood. Over time, the condition can lead to muscle deterioration. Here, recognizing the symptoms of DMD in time is crucial for seeking an early diagnosis and appropriate management options to slow down disease progression. So, here are a few things to know about the disorder: What is DMD? Duchenne Muscular Dystrophy is a genetic disorder characterized by the progressive weakening and wasting of muscles. It is one of the most common forms of muscular dystrophy, and it primarily affects young males. DMD is caused by mutations in the dystrophin gene that lead to the absence or dysfunction of dystrophin—a protein vital for muscle stability. This is an X-linked recessive disorder, meaning it primarily affects males. So, females can be carriers of the mutated gene without experiencing any symptoms, but males born to carrier mothers have a 50% chance of inheriting the mutated gene and developing DMD. Symptoms DMD often presents its initial symptoms in early childhood, usually between the ages of 2 and 4. So, it is important to keep an eye out for signs such as delayed motor milestones, difficulty standing, and frequent falls.
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14 early signs of heartburn to watch out for

14 early signs of heartburn to watch out for

Heartburn is a prevalent condition that affects millions of people worldwide. The burning feeling in the chest caused by the onset of heartburn can cause discomfort. The condition can be temporary or chronic if left unmanaged. It occurs when stomach acid flows back into the esophagus, causing irritation and discomfort. Recognizing the early symptoms of heartburn is crucial for timely intervention and effective management. Let’s look at the subtle indicators of heartburn. What is heartburn? Heartburn, known as acid indigestion or acid reflux, is a condition where the stomach acid rushes back up into the esophagus (a tube carrying food from the mouth to the stomach, and it is not designed to handle the corrosive effects of stomach acid). The acid reflux generally leads to a range of uncomfortable symptoms. The primary reason behind heartburn is a dysfunctional lower esophageal sphincter (LES). It is a muscle ring situated at the bottom of the esophagus that normally acts as a one-way valve, allowing foods and liquids to enter the stomach while preventing stomach contents from flowing back up into the esophagus. When the LES weakens or relaxes inappropriately, stomach acid can escape into the esophagus, leading to heartburn. Early symptoms of heartburn Burning sensation in the chest This is a common sign of the condition, often erupting from behind the breastbone.
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11 common migraine causing odors

11 common migraine causing odors

Migraine is a neurological disorder characterized by severe, pulsating headaches often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. While the exact cause of migraines remains elusive, various triggers have been identified, including certain odors. Odor-triggered migraines can be particularly challenging to manage and treat. Below are some familiar smells that may trigger the condition, simple strategies to cope with them, and other factors that can trigger migraines. Why do certain odors cause migraine? The phenomenon of migraine headaches due to odor sensitivity is called osmophobia or olfactory migraines. The exact mechanism by which odors trigger migraines is not fully understood, but several theories exist. One is sensory overload, wherein strong odors overload the brain’s sensory processing, leading to a migraine in individuals susceptible to sensory triggers. Some people may also have heightened sensitivity to certain chemicals found in odorous substances. When exposed to these chemicals, their bodies may react with a migraine. Lastly, odors can activate specific neural pathways in the brain, potentially triggering migraine pathways in those predisposed to migraines. Odors that may trigger migraine Perfumes and fragrances Perfumes and strong fragrances are among the most common migraine triggers. The synthetic chemicals in many perfumes can overwhelm the olfactory system, leading to migraines in susceptible individuals.
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Herpes simplex virus – Symptoms, causes, and management

Herpes simplex virus – Symptoms, causes, and management

Herpes simplex virus (HSV), commonly known as herpes, is an infection that may result in painful blisters or ulcers. The disease is primarily spread through skin-to-skin contact. There are two types of the herpes simplex virus, type 1 and type 2. According to researchers, around 3.7 billion people under age 50 are diagnosed with herpes simplex virus type 1 (HSV-1) infection, and about 491 million aged 15 to 49 globally with herpes simplex virus type 2 (HSV-2) infection. Symptoms There are a few things that one should note about the symptoms of the herpes simplex virus. Most people with herpes do not experience any symptoms or only mild symptoms. Others might not even be aware that they have the infection and may pass it along to others unknowingly. The symptoms of the condition may include painful, recurring blisters or ulcers. Furthermore, new infections may result in body aches, a fever, and swollen lymph nodes. An individual with the disease might experience varied symptoms during the first episode of infection than when it recurs. If symptoms occur, they might begin with itching, tingling, or burning sensations near where the sores appear. The common symptoms of oral herpes include blisters (cold sores) or open sores (ulcers) around the mouth or lips.
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Nail fungal infection – Causes, symptoms, and management

Nail fungal infection – Causes, symptoms, and management

Fungus is normally present in the body, but when there is an overgrowth, it can lead to infection. One common infection is nail fungal infection, or onychomycosis or tinea unguium. It usually affects the toenails rather than the fingernails, causing them to become brittle and discolored. This infection develops over time, so any changes to the affected nails may be subtle initially. Here are some common types, causes, symptoms, and treatment measures for nail fungal infections. Types of nail fungal infections In general, there are four types of nail fungal infections. Distal or lateral subungual onychomycosis This is a common nail fungal infection caused by a type of fungus known as dermatophyte. This infection can occur in both toenails and fingernails. It usually starts as a yellowish-colored patch in the nail bed, right under the nail. Over time, this patch spreads to the center of the nail from the edges, causing the nail to separate from the nail bed. Candidal onychomycosis This type of infection is caused by yeast. It mostly occurs in the fingernails. The yeast causes the area around the infected nail to become inflamed and swollen. Sometimes, the nail might come off entirely from the nail bed.
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Bipolar disorder – Its types and early signs

Bipolar disorder – Its types and early signs

Bipolar disorder is a mental health disorder characterized by extreme moods, either significantly high or low. The high periods are referred to as mania or hypomania, and the low moods are called depression. However, the moods can sometimes be concurrent, meaning individuals with bipolar disorder may have manic and depressive symptoms at once. The condition is usually difficult to diagnose; however, some signs can detect bipolar disorder early, and treatment can be started accordingly. Types and symptoms Often, the signs and symptoms of bipolar disorder overlap with those of other conditions, so it becomes difficult to diagnose it timely, which can delay treatment. However, there are now some criteria laid out by the Diagnostic and Statistical Manual of Mental Disorders that help recognize bipolar disorder. There are four types of bipolar disorders, and the symptoms vary according to the type of the condition. These are as follows: 1. Bipolar I This type is diagnosed when the individual experiences manic episodes. The symptoms are as follows: This includes a significant shift in the behavior and mood of the person. These mood changes are often unlike the person’s personality or usual behavior, making it evident that something is wrong. A manic episode is also considered manic when it is present most of the day and nearly daily.
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12 surprising facts about COPD to know

12 surprising facts about COPD to know

Chronic Obstructive Pulmonary Disease, also known as COPD, is a well-recognized respiratory ailment that affects millions of lives worldwide. COPD, characterized by symptoms like chronic cough, shortness of breath, and reduced lung function, is a complex condition with multiple layers. While its core features are understood by many, an array of surprising and often overlooked facets surrounds this condition. This article delves into these lesser-known aspects of COPD to comprehensively understand the disease. Underdiagnosed and misdiagnosed cases One of the most surprising facts about COPD is the prevalence of underdiagnosed and misdiagnosed cases. According to the World Health Organization (WHO), more than 90% of COPD cases are estimated to remain undiagnosed. This is partly because early symptoms, such as coughing and shortness of breath, are often attributed to the natural aging process or other respiratory conditions. Additionally, many individuals with COPD do not seek attention until the disease has progressed significantly. Impact on mental health COPD not only affects physical health but also takes a toll on mental well-being. Surprisingly, individuals with COPD are more likely to experience anxiety and depression. The disease’s chronic nature and its impact on daily activities and social interactions may lead to isolation and sadness.
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7 lesser-known signs of multiple myeloma

7 lesser-known signs of multiple myeloma

Multiple myeloma is a type of cancer that primarily affects the plasma cells found in the bone marrow. Plasma cells typically produce antibodies to help the body fight infections. However, in multiple myeloma, certain plasma cells become cancerous and start to multiply uncontrollably, crowding out healthy blood-forming cells in the bone marrow. These cancerous plasma cells can produce abnormal proteins, which can accumulate in the blood and urine, leading to various health problems. Here are the lesser-known signs of multiple myeloma: Recurrent infections Multiple myeloma weakens the immune system, making individuals more susceptible to infections. However, this sign is often overlooked or attributed to other causes. Recurring or persistent infections, such as respiratory infections, urinary tract infections, or skin infections, can be an early indication of an underlying immune system dysfunction caused by multiple myeloma. The connection between multiple myeloma and infections lies in the disease’s impact on plasma cells’ production of antibodies. As the cancerous plasma cells multiply in the bone marrow, they crowd out healthy cells responsible for producing antibodies, impairing the body’s ability to fight infections effectively. Recognizing the link between recurring infections and multiple myeloma can lead to earlier diagnosis and treatment, which may improve the patient’s overall prognosis.
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9 tips for changing the oil and filter on Dodge vehicles

9 tips for changing the oil and filter on Dodge vehicles

Dodge is a famous automobile manufacturer with an excellent lineup of trucks and SUVs. While its vehicles are known for performance and durability, they must be maintained well. A fundamental aspect of car upkeep is changing the oil and filters regularly. Whether one owns a robust Dodge truck or a versatile SUV, understanding the nuances of oil and filter changes can help the automobile run smoothly and extend its lifespan. The function of oil and filters in a vehicle Engine oil is a lubricating fluid that circulates throughout the engine to reduce friction between moving parts, dissipate heat, and protect against wear and tear. The oil filter is responsible for removing impurities and contaminants from the engine oil. The filter is replaced during routine oil changes to maintain its filtration capabilities. Tips for changing oil and filters in vehicles Oil and filters play crucial roles in the vehicle’s engine, ensuring it operates efficiently and remains in good condition. If one follows these tips, it will not only ensure engine longevity but also contribute to better fuel efficiency and reduced emissions: Use the right tools and materials Before starting, it’s important to gather all the right tools. One will need an oil filter wrench to remove the old filter, a container to catch the old oil (like an oil drain pan), a set of sockets or wrenches, a funnel to pour in new oil, a new oil filter, and the right type and sufficient amount of oil.
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25 signs and symptoms of pneumonia to know of

25 signs and symptoms of pneumonia to know of

Pneumonia is a common respiratory infection that can affect people of all ages, causing various symptoms that vary in severity. At the same time, many are familiar with the hallmark signs such as fever and cough, shortness of breath, chest pain, and numerous other indicators that can point to pneumonia. This comprehensive article thoroughly explores pneumonia’s signs and symptoms, helping individuals recognize the condition early and seek appropriate medical care. Fever Fever is one of the most prevalent symptoms of pneumonia. It typically presents with a high body temperature, often exceeding 100.4°F (38°C). Fever is the body’s natural response to infection and signifies that the immune system is actively fighting the pneumonia-causing pathogens. Cough A persistent cough is another hallmark symptom. It can produce different types of mucus, including yellow, green, or bloody. The cough may be accompanied by chest pain or discomfort ranging from mild to severe. Shortness of breath Many individuals with pneumonia experience shortness of breath, particularly when engaging in physical activities. This symptom occurs due to the inflammation and infection within the lungs, making it challenging for the respiratory system to function optimally. Chest pain Chest pain is often described as a sharp or stabbing sensation typically felt on the side of the affected lung.
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